FcRn Overexpression in Transgenic Mice Results in Augmented APC Activity and Robust Immune Response with Increased Diversity of Induced Antibodies

Our previous studies have shown that overexpression of bovine FcRn (bFcRn) in transgenic (Tg) mice leads to an increase in the humoral immune response, characterized by larger numbers of Ag-specific B cells and other immune cells in secondary lymphoid organs and higher levels of circulating Ag-speci...

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Detalles Bibliográficos
Autores principales: Végh, Attila, Farkas, Anita, Kövesdi, Dorottya, Papp, Krisztián, Cervenak, Judit, Schneider, Zita, Bender, Balázs, Hiripi, László, László, Glória, Prechl, József, Matkó, János, Kacskovics, Imre
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340356/
https://ncbi.nlm.nih.gov/pubmed/22558422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036286
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