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Leucine-rich Repeat and WD Repeat-containing Protein 1 Is Recruited to Pericentric Heterochromatin by Trimethylated Lysine 9 of Histone H3 and Maintains Heterochromatin Silencing

Lrwd1, a protein containing a leucine-rich repeat and a WD40 repeat domain, interacts with the origin replication complex (ORC), a protein complex involved in both initiation of DNA replication and heterochromatin silencing. Lrwd1 and ORC are known to co-purify with repressive histone marks (trimeth...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Chan, Kui Ming, Zhang, Zhiguo
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340258/
https://ncbi.nlm.nih.gov/pubmed/22427655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.337980
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