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WD40 Repeats Arrange Histone Tails for Spreading of Silencing
Direct binding of WD40 repeat of Embryonic Ectoderm Development (EED) in the Polycomb Repressor Complex 2 (PRC2) to the histone H3 tail regulates the H3K27 methyltrasnferase activity of PRC2. The binding activity is required for the methylation of H3K27 over long distance of a Drosophila chromosome...
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| Publié dans: | J Mol Cell Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6283120/ https://ncbi.nlm.nih.gov/pubmed/20008334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjp046 |
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