Membrane Topology and Intracellular Processing of Cyclin M2 (CNNM2)

Recently, mutations in the cyclin M2 (CNNM2) gene were identified to be causative for severe hypomagnesemia. In kidney, CNNM2 is a basolaterally expressed protein with predominant expression in the distal convoluted tubule. Transcellular magnesium (Mg(2+)) reabsorption in the distal convoluted tubul...

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Detalhes bibliográficos
Main Authors: de Baaij, Jeroen H. F., Stuiver, Marchel, Meij, Iwan C., Lainez, Sergio, Kopplin, Kathrin, Venselaar, Hanka, Müller, Dominik, Bindels, René J. M., Hoenderop, Joost G. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340180/
https://ncbi.nlm.nih.gov/pubmed/22399287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.342204
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