Structural and Biochemical Characterization of Glycoside Hydrolase Family 79 β-Glucuronidase from Acidobacterium capsulatum

We present the first structure of a glycoside hydrolase family 79 β-glucuronidase from Acidobacterium capsulatum, both as a product complex with β-d-glucuronic acid (GlcA) and as its trapped covalent 2-fluoroglucuronyl intermediate. This enzyme consists of a catalytic (β/α)(8)-barrel domain and a β-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Michikawa, Mari, Ichinose, Hitomi, Momma, Mitsuru, Biely, Peter, Jongkees, Seino, Yoshida, Makoto, Kotake, Toshihisa, Tsumuraya, Yoichi, Withers, Stephen G., Fujimoto, Zui, Kaneko, Satoshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Enzymology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340155/
https://ncbi.nlm.nih.gov/pubmed/22367201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.346288
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