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Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

Infusion of the chemotherapeutic agent oxaliplatin leads to an acute and a chronic form of peripheral neuropathy. Acute oxaliplatin neuropathy is characterized by sensory paresthesias and muscle cramps that are notably exacerbated by cooling. Painful dysesthesias are rarely reported for acute oxalip...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sittl, Ruth, Lampert, Angelika, Huth, Tobias, Schuy, E. Theresa, Link, Andrea S., Fleckenstein, Johannes, Alzheimer, Christian, Grafe, Peter, Carr, Richard W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340057/
https://ncbi.nlm.nih.gov/pubmed/22493249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118058109
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