Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

Infusion of the chemotherapeutic agent oxaliplatin leads to an acute and a chronic form of peripheral neuropathy. Acute oxaliplatin neuropathy is characterized by sensory paresthesias and muscle cramps that are notably exacerbated by cooling. Painful dysesthesias are rarely reported for acute oxalip...

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Detaylı Bibliyografya
Asıl Yazarlar: Sittl, Ruth, Lampert, Angelika, Huth, Tobias, Schuy, E. Theresa, Link, Andrea S., Fleckenstein, Johannes, Alzheimer, Christian, Grafe, Peter, Carr, Richard W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340057/
https://ncbi.nlm.nih.gov/pubmed/22493249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118058109
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