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Cap Snatching of Yeast L-A Double-stranded RNA Virus Can Operate in Trans and Requires Viral Polymerase Actively Engaging in Transcription

Eukaryotic mRNA bears a cap structure (m(7)GpppX-) at the 5′ terminus crucial for efficient translation and stability. The yeast L-A double-stranded RNA virus furnishes its mRNA with this structure by a novel cap-snatching mechanism in which the virus transfers an m(7)Gp moiety from host mRNA to the...

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Detalhes bibliográficos
Main Authors: Fujimura, Tsutomu, Esteban, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340004/
https://ncbi.nlm.nih.gov/pubmed/22367202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.327676
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