Structural Domains Required for Caenorhabditis elegans G Protein-coupled Receptor Kinase 2 (GRK-2) Function in Vivo

G protein-coupled receptor kinases (GRKs) are key regulators of signal transduction that specifically phosphorylate activated G protein-coupled receptors (GPCRs) to terminate signaling. Biochemical and crystallographic studies have provided great insight into mammalian GRK2/3 interactions and struct...

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Hlavní autoři: Wood, Jordan F., Wang, Jianjun, Benovic, Jeffrey L., Ferkey, Denise M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339999/
https://ncbi.nlm.nih.gov/pubmed/22375004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.336818
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