A Novel Cardiomyocyte-enriched MicroRNA, miR-378, Targets Insulin-like Growth Factor 1 Receptor: IMPLICATIONS IN POSTNATAL CARDIAC REMODELING AND CELL SURVIVAL

Postnatal cardiac remodeling is characterized by a marked decrease in the insulin-like growth factor 1 (IGF1) and IGF1 receptor (IGF1R) expression. The underlying mechanism remains unexplored. This study examined the role of microRNAs in postnatal cardiac remodeling. By expression profiling, we obse...

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Bibliographische Detailangaben
Hauptverfasser: Knezevic, Ivana, Patel, Aalok, Sundaresan, Nagalingam R., Gupta, Mahesh P., Solaro, R. John, Nagalingam, Raghu S., Gupta, Madhu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339988/
https://ncbi.nlm.nih.gov/pubmed/22367207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.331751
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