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Roles of Telomerase Reverse Transcriptase N-terminal Domain in Assembly and Activity of Tetrahymena Telomerase Holoenzyme

Telomerase extends chromosome ends by the addition of single-stranded telomeric repeats. To support processive repeat synthesis, it has been proposed that coordination occurs between DNA interactions with the telomerase RNA template, the active site in the telomerase reverse transcriptase (TERT) cor...

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Hlavní autoři: Eckert, Barbara, Collins, Kathleen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339965/
https://ncbi.nlm.nih.gov/pubmed/22367200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339853
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