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Prospective Assessment of Genetic Effects on Progression to Different Stages of Age-Related Macular Degeneration Using Multistate Markov Models

PURPOSE. Understanding the effect of genes on progression to different stages of age-related macular degeneration (AMD) may suggest stage-specific therapeutic targets and more precise prediction of the development of this disease. METHODS. Progression events and time to each stage of AMD were derive...

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Hlavní autoři: Yu, Yi, Reynolds, Robyn, Rosner, Bernard, Daly, Mark J., Seddon, Johanna M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Association for Research in Vision and Ophthalmology, Inc. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339916/
https://ncbi.nlm.nih.gov/pubmed/22247473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8657
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