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Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin

Dynamic rearrangement of actin filament networks is critical for cell motility, phagocytosis and endocytosis. Coronins facilitate these processes, in part, by their ability to bind F-actin (filamentous actin). We previously identified a conserved surface-exposed arginine (Arg(30)) in the β-propeller...

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Detalhes bibliográficos
Main Authors: Chan, Keefe T., Roadcap, David W., Holoweckyj, Nicholas, Bear, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339874/
https://ncbi.nlm.nih.gov/pubmed/22364218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120209
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