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High-throughput Screening and Biosensing with Fluorescent C. elegans Strains

High-throughput screening (HTS) is a powerful approach for identifying chemical modulators of biological processes. However, many compounds identified in screens using cell culture models are often found to be toxic or pharmacologically inactive in vivo(1-2). Screening in whole animal models can hel...

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Detalhes bibliográficos
Main Authors: Leung, Chi K., Deonarine, Andrew, Strange, Kevin, Choe, Keith P.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339844/
https://ncbi.nlm.nih.gov/pubmed/21633332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2745
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