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Ets2 regulates colonic stem cells and sensitivity to tumorigenesis

Ets2 has both tumor repressive and supportive functions for different types of cancer. We have investigated the role of Ets2 within intestinal epithelial cells in postnatal mouse colon development and tumorigenesis. Conditional inactivation of Ets2 within intestinal epithelial cells results in over...

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Autors principals: Múnera, Jorge, Cecena, Grace, Jedlicka, Paul, Wankell, Miriam, Oshima, Robert G.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339631/
https://ncbi.nlm.nih.gov/pubmed/21425406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.599
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