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Differential Sensitivity of Mouse Epithelial Tissues to the Polyomavirus Middle T Oncogene

To determine how different epithelial cell types respond to the same oncogenic stimulation, we have used a modified human keratin 18 gene to conditionally express the polyomavirus middle T antigen (PyMT) oncogene in simple epithelial tissues of transgenic mice. Activation of PyMT expression by trans...

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Detalhes bibliográficos
Main Authors: Cecena, Grace, Wen, Fang, Cardiff, Robert D., Oshima, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592648/
https://ncbi.nlm.nih.gov/pubmed/16400032
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