Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood–Brain Barrier Damage in Early Ischemic Stroke Stage

Blood–brain barrier (BBB) disruption occurs early enough to be within the thrombolytic time window, and this early ischemic BBB damage is closely associated with hemorrhagic transformation and thus emerging as a promising target for reducing the hemorrhagic complications of thrombolytic stroke thera...

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Autori principali: Liu, Jie, Jin, Xinchun, Liu, Ke J., Liu, Wenlan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339570/
https://ncbi.nlm.nih.gov/pubmed/22378877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6409-11.2012
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