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Differential Effects of Tautomycetin and Its Derivatives on Protein Phosphatase Inhibition, Immunosuppressive Function and Antitumor Activity

In the present work, we studied the structure-activity relationship (SAR) of tautomycetin (TMC) and its derivatives. Further, we demonstrated the correlation between the immunosuppressive fuction, anticancer activity and protein phosphatase type 1 (PP1) inhibition of TMC and its derivatives. We have...

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Detalhes bibliográficos
Main Authors: Niu, Mingshan, Sun, Yan, Liu, Bo, Tang, Li, Qiu, Rongguo
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339291/
https://ncbi.nlm.nih.gov/pubmed/22563261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2012.16.2.145
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