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COSA-1 Reveals Separable Licensing and Reinforcement Steps and Efficient Homeostasis Governing Meiotic Crossovers
Crossovers (COs) between homologous chromosomes ensure their faithful segregation during meiosis. We identify C. elegans COSA-1 as a key component required to convert double-strand breaks (DSBs) into COs. COSA-1 localizes to foci during late meiotic prophase that correspond to the single CO site on...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339199/ https://ncbi.nlm.nih.gov/pubmed/22464324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.052 |
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