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Promiscuous Processing of Human α/β-Protryptases by Cathepsins L, B, and C
Human α- and β-protryptase zymogens are abundantly and selectively produced by mast cells, but the mechanism(s) by which they are processed is uncertain. β-Protryptase is sequentially processed in vitro by autocatalysis at R(−3) followed by cathepsin (CTS) C proteolysis to the mature enzyme. However...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339195/ https://ncbi.nlm.nih.gov/pubmed/21562164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001804 |
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