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Oxalyl-CPG: a labile support for synthesis of sensitive oligonucleotide derivatives.

A procedure is described for linking nucleosides covalently to controlled pore glass or cross-linked polystyrene supports by means of an oxalyl anchor. Though stable to triethylamine and diisopropylamine, the nucleoside-oxalyl link can be cleaved within a few minutes at room temperature with ammoniu...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Alul, R H, Singman, C N, Zhang, G R, Letsinger, R L
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1991
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2027761/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.7.1527
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