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Oxalyl-CPG: a labile support for synthesis of sensitive oligonucleotide derivatives.
A procedure is described for linking nucleosides covalently to controlled pore glass or cross-linked polystyrene supports by means of an oxalyl anchor. Though stable to triethylamine and diisopropylamine, the nucleoside-oxalyl link can be cleaved within a few minutes at room temperature with ammoniu...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
1991
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC333911/ https://ncbi.nlm.nih.gov/pubmed/2027761 |
| Etykiety: |
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