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Effect of uracil situated in the vicinity of a mispair on the directionality of mismatch correction in Escherichia coli.

We wanted to establish whether strand breaks and gaps, arising during the removal of uracil from newly-synthesized DNA, can be utilized as strand discrimination signals by the methyl-directed mismatch repair system of Escherichia coli. For this purpose, we constructed a series of M13 heteroduplexes...

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Détails bibliographiques
Auteurs principaux: Aprelikova, O, Jiricny, J
Format: Artigo
Langue:Inglês
Publié: 1991
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC333899/
https://ncbi.nlm.nih.gov/pubmed/2027752
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