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Synthesis and selective cleavage of an oligodeoxynucleotide containing a bridged internucleotide 5'-phosphorothioate linkage.

A self complementary oligodeoxynucleotide dodecamer containing an achiral bridged 5'-phosphorothioate linkage 3'-O-P-S-5' has been prepared using the solid phase phosphoramidite procedure. For the incorporation of the phosphorothioate link we have used a 5'-(S-trityl)-mercapto-5'-deoxythymidine-3'-p...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Principais autores: Mag, M, Lüking, S, Engels, J W
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1991
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2027751/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.7.1437
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