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Synthesis of hexanucleotide analogues containing diisopropylsilyl internucleotide linkages.

The synthesis of two silyl-linked hexanucleotide analogues is described. Hypochromicity and CD measurements indicate that the thymidine hexanucleotide analogue bears a strong resemblance to its phosphodiester-linked counterpart.

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Bibliographic Details
Main Authors: Cormier, J F, Ogilvie, K K
Format: Artigo
Language:Inglês
Published: 1988
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC336650/
https://ncbi.nlm.nih.gov/pubmed/3380689
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