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Two-steps control of cellular prion physiology by the extracellular regulated kinase-1 (ERK1)
Cellular prion (PrP(C)) undergoes a regulated α-secretase-like cleavage by the disintegrin ADAM17 similar to the one taking place on β-Amyloid Precursor Protein (βAPP). Because these cleavages give rise to biologically active fragments, understanding their regulation could be of importance. We have...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338960/ https://ncbi.nlm.nih.gov/pubmed/22453173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.6.1.18004 |
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