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Hypersensitive site 4 of the human beta globin locus control region.

The Locus Control Region (LCR) of the human beta globin gene domain is defined by four erythroid-specific DNasel hypersensitive sites (HSS) located upstream of this multigene cluster. The LCR confers copy number dependent high levels of erythroid specific expression to a linked transgene, independen...

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Bibliografiske detaljer
Main Authors: Pruzina, S, Hanscombe, O, Whyatt, D, Grosveld, F, Philipsen, S
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC333894/
https://ncbi.nlm.nih.gov/pubmed/2027748
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