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NMR studies of a DNA containing 8-hydroxydeoxyguanosine.

The effects of hydroxylation at the C8 of a deoxyguanosine residue in DNA were studied by NMR analysis of a self-complementary dodecanucleotide, d(C1-G2-C3-oh8G4-A5-A6-T7-T8-C9-G10-C11-G12), which has an 8-hydroxy-2'-deoxyguanosine (oh8dG) residue at the 4th position. NMR data indicate that the...

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Detalhes bibliográficos
Main Authors: Oda, Y, Uesugi, S, Ikehara, M, Nishimura, S, Kawase, Y, Ishikawa, H, Inoue, H, Ohtsuka, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC333893/
https://ncbi.nlm.nih.gov/pubmed/2027747
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