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A Toll-like Receptor 1 Polymorphism Is Associated with Heightened T-helper 1 Inflammatory Responses and Antibiotic-Refractory Lyme Arthritis

OBJECTIVE: Single-nucleotide polymorphisms (SNPs) have been identified in several genes encoding Toll-like receptors (TLRs) that alter immune function, inflammatory responses and disease susceptibility. The SNPs with best evidence for affecting immune function are TLR1 (1805GG), TLR2 (2258GA) and TL...

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Bibliografiske detaljer
Main Authors: Strle, Klemen, Shin, Junghee J., Glickstein, Lisa J., Steere, Allen C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338893/
https://ncbi.nlm.nih.gov/pubmed/22246581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34383
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