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A Toll-like Receptor 1 Polymorphism Is Associated with Heightened T-helper 1 Inflammatory Responses and Antibiotic-Refractory Lyme Arthritis
OBJECTIVE: Single-nucleotide polymorphisms (SNPs) have been identified in several genes encoding Toll-like receptors (TLRs) that alter immune function, inflammatory responses and disease susceptibility. The SNPs with best evidence for affecting immune function are TLR1 (1805GG), TLR2 (2258GA) and TL...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338893/ https://ncbi.nlm.nih.gov/pubmed/22246581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34383 |
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