The Novel Endocrine Disruptor Tolylfluanid Impairs Insulin Signaling in Primary Rodent and Human Adipocytes through a Reduction in Insulin Receptor Substrate-1 Levels

Emerging data suggest that environmental endocrine disrupting chemicals (EDCs) may contribute to the pathophysiology of obesity and diabetes. In prior work, the phenylsulfamide fungicide tolylfluanid (TF) was shown to augment adipocyte differentiation, yet its effects on mature adipocyte metabolism...

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Detaylı Bibliyografya
Asıl Yazarlar: Sargis, Robert M., Neel, Brian A., Brock, Clifton O., Lin, Yuxi, Hickey, Allison T., Carlton, Daniel A., Brady, Matthew J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338892/
https://ncbi.nlm.nih.gov/pubmed/22387882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.02.015
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