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Clinical Utility of LC3 and p62 Immunohistochemistry in Diagnosis of Drug-Induced Autophagic Vacuolar Myopathies: A Case-Control Study

BACKGROUND: Some patients treated with chloroquine, hydroxychloroquine, or colchicine develop autophagic vacuolar myopathy, the diagnosis of which currently requires electron microscopy. The goal of the current study was to develop an immunohistochemical diagnostic marker for this pathologic entity....

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Detalhes bibliográficos
Main Authors: Lee, Han S., Daniels, Brianne H., Salas, Eduardo, Bollen, Andrew W., Debnath, Jayanta, Margeta, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338695/
https://ncbi.nlm.nih.gov/pubmed/22558391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036221
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