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Dysregulated Recruitment of the Histone Methyltransferase EZH2 to the Class II Transactivator (CIITA) Promoter IV in Breast Cancer Cells

One mechanism frequently utilized by tumor cells to escape immune system recognition and elimination is suppression of cell surface expression of Major Histocompatibility Class II (MHC II) molecules. Expression of MHC II is regulated primarily at the level of transcription by the Class II Transactiv...

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Detalles Bibliográficos
Main Authors: Truax, Agnieszka D., Thakkar, Meghna, Greer, Susanna F.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338556/
https://ncbi.nlm.nih.gov/pubmed/22563434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036013
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