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Molecular Dynamics Simulation of the Complex PBP-2x with Drug Cefuroxime to Explore the Drug Resistance Mechanism of Streptococcus suis R61

Drug resistance of Streptococcus suis strains is a worldwide problem for both humans and pigs. Previous studies have noted that penicillin-binding protein (PBPs) mutation is one important cause of β-lactam antibiotic resistance. In this study, we used the molecular dynamics (MD) method to study the...

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Bibliographische Detailangaben
Hauptverfasser: Ge, Yan, Wu, Jiayan, Xia, Yingjie, Yang, Ming, Xiao, Jingfa, Yu, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338546/
https://ncbi.nlm.nih.gov/pubmed/22563422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035941
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