Characterization of Spectinomycin Resistance in Streptococcus suis Leads to Two Novel Insights into Drug Resistance Formation and Dissemination Mechanism

Spectinomycin is an aminocyclitol antibiotic used clinically to treat a variety of infections in animals. Here, we characterized drug resistance prevalence in clinical Streptococcus suis isolates and discovered a novel resistance mechanism in which the s5 mutation (Gly26Asp) results in high spectino...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Huang, Kaisong, Zhang, Qiang, Song, Yajing, Zhang, Zhewen, Zhang, Anding, Xiao, Jingfa, Jin, Meilin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038275/
https://ncbi.nlm.nih.gov/pubmed/27458226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01157-16
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