Cyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic mice

BACKGROUND: Intensive light exposure and beta-amyloid (Aβ) aggregates have been known as a risk factor for macular degeneration and an important component in the pathologic drusen structure involved in this disorder, respectively. However, it is unknown whether Aβ deposition mediates or exacerbates...

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Bibliografiske detaljer
Main Authors:	Dong, Zhizhang, Li, Juan, Leng, Yunxia, Sun, Xuerong, Hu, Huiling, He, Yuan, Tan, Zhiqun, Ge, Jian
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2012
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3338397/ https://ncbi.nlm.nih.gov/pubmed/22443196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-34
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Cyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic mice

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