Chronic Inhibition of Epidermal Growth Factor Receptor Tyrosine Kinase and Extracellular Signal-Regulated Kinases 1 and 2 (ERK1/2) Augments Vascular Response to Limb Ischemia in Type 2 Diabetic Mice

Type 2 diabetes is a key risk factor for ischemia-dependent pathology; therefore, a significant medical need exists to develop novel therapies that increase the formation of new vessels. We explored the therapeutic potential of epidermal growth factor receptor tyrosine kinase (EGFRtk) and extracellu...

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Hlavní autoři: Choi, Soo-Kyoung, Galán, Maria, Partyka, Megan, Trebak, Mohamed, Belmadani, Souad, Matrougui, Khalid
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2012
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338339/
https://ncbi.nlm.nih.gov/pubmed/22067908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.09.016
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