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NF-κB as potential target in the treatment of melanoma
The RAS/MAP kinase pathway has attracted attention because activating mutations of the BRAF serine/threonine kinase was described in over 50% of melanomas. Very recently, selective and potent BRAF inhibitors have been developed. Several other signal transduction pathways have been found to be consti...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338086/ https://ncbi.nlm.nih.gov/pubmed/22433222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-53 |
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