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NF-κB as potential target in the treatment of melanoma

The RAS/MAP kinase pathway has attracted attention because activating mutations of the BRAF serine/threonine kinase was described in over 50% of melanomas. Very recently, selective and potent BRAF inhibitors have been developed. Several other signal transduction pathways have been found to be consti...

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Bibliografiske detaljer
Main Authors: Madonna, Gabriele, Ullman, Claudio Dansky, Gentilcore, Giusy, Palmieri, Giuseppe, Ascierto, Paolo Antonio
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338086/
https://ncbi.nlm.nih.gov/pubmed/22433222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-53
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