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Convergence and coevolution of Hepatitis B virus drug resistance
Treatment with lamivudine of patients infected with hepatitis B virus (HBV) results in a high rate of drug resistance, which is primarily associated with the rtM204I/V substitution in the HBV reverse transcriptase domain. Here we show that the rtM204I/V substitution, although essential, is insuffici...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337990/ https://ncbi.nlm.nih.gov/pubmed/22510694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1794 |
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