Coevolution of the Hepatitis C Virus Polyprotein Sites in Patients on Combined Pegylated Interferon and Ribavirin Therapy

Genotype-specific sensitivity of the hepatitis C virus (HCV) to interferon-ribavirin (IFN-RBV) combination therapy and reduced HCV response to IFN-RBV as infection progresses from acute to chronic infection suggest that HCV genetic factors and intrahost HCV evolution play important roles in therapy...

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Bibliografiske detaljer
Main Authors: Lara, James, Xia, Guoliang, Purdy, Mike, Khudyakov, Yury
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Genetic Diversity and Evolution
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067842/
https://ncbi.nlm.nih.gov/pubmed/21248044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02197-10
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