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Coevolution of the Hepatitis C Virus Polyprotein Sites in Patients on Combined Pegylated Interferon and Ribavirin Therapy
Genotype-specific sensitivity of the hepatitis C virus (HCV) to interferon-ribavirin (IFN-RBV) combination therapy and reduced HCV response to IFN-RBV as infection progresses from acute to chronic infection suggest that HCV genetic factors and intrahost HCV evolution play important roles in therapy...
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Autori principali: | , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Microbiology (ASM)
2011
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067842/ https://ncbi.nlm.nih.gov/pubmed/21248044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02197-10 |
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