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A Novel Bayesian Graphical Model for Genome-Wide Multi-SNP Association Mapping

Most disease association mapping algorithms are based on hypothesis testing procedures that test one variant at a time. Those methods lose power when the disease mutations are jointly tagged by multiple variants, or when gene-gene interaction exist. Nearby variants are also correlated, for which pro...

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Detalhes bibliográficos
Autor principal: Zhang, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337957/
https://ncbi.nlm.nih.gov/pubmed/22127647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20661
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