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A Novel Bayesian Graphical Model for Genome-Wide Multi-SNP Association Mapping
Most disease association mapping algorithms are based on hypothesis testing procedures that test one variant at a time. Those methods lose power when the disease mutations are jointly tagged by multiple variants, or when gene-gene interaction exist. Nearby variants are also correlated, for which pro...
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| Format: | Artigo |
| Jezik: | Inglês |
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2011
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337957/ https://ncbi.nlm.nih.gov/pubmed/22127647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20661 |
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