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Inflammation and mortality in a frail mouse model

Mice homozygous for targeted deletion of the interleukin 10 gene (Il-10) have been partially characterized as a model for human frailty. These mice have increased serum interleukin (IL)-6 in midlife, skeletal muscle weakness, and an altered skeletal muscle gene expression profile compared to age and...

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Detalhes bibliográficos
Main Authors: Ko, Fred, Yu, Qilu, Xue, Qian-Li, Yao, Wenliang, Brayton, Cory, Yang, Huanle, Fedarko, Neal, Walston, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337927/
https://ncbi.nlm.nih.gov/pubmed/21633802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9269-6
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