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Inflammation and mortality in a frail mouse model
Mice homozygous for targeted deletion of the interleukin 10 gene (Il-10) have been partially characterized as a model for human frailty. These mice have increased serum interleukin (IL)-6 in midlife, skeletal muscle weakness, and an altered skeletal muscle gene expression profile compared to age and...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Netherlands
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337927/ https://ncbi.nlm.nih.gov/pubmed/21633802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9269-6 |
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