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Upregulated ex vivo expression of stress-responsive inflammatory pathway genes by LPS-challenged CD14(+) monocytes in frail older adults

Frailty has been increasingly recognized as an important clinical syndrome in old age. The frailty syndrome is characterized by chronic inflammation, decreased functional and physiologic reserve, and increased vulnerability to stressors, leading to disability and mortality. However, molecular mechan...

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Detalhes bibliográficos
Main Authors: Qu, Tao, Walston, Jeremy D., Yang, Huanle, Fedarko, Neal S., Xue, Qian-Li, Beamer, Brock A., Ferrucci, Luigi, Rose, Noel R., Leng, Sean X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673566/
https://ncbi.nlm.nih.gov/pubmed/19027777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2008.10.005
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