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The transcription factor LF-A1 interacts with a bipartite recognition sequence in the promoter regions of several liver-specific genes.

The transcription factors LF-A1 and LF-B1 are required for the cell-specific expression of the human alpha 1-antitrypsin gene in hepatocytes. We report here the purification and preliminary characterization of LF-A1. This protein, purified to homogeneity from calf liver nuclei by site-specific DNA a...

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Main Authors: Ramji, D P, Tadros, M H, Hardon, E M, Cortese, R
Formato: Artigo
Idioma:Inglês
Publicado: 1991
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC333792/
https://ncbi.nlm.nih.gov/pubmed/2020548
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