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The binding site for the liver-specific transcription factor Tf-LF1 and the TATA box of the human transferrin gene promoter are the only elements necessary to direct liver-specific transcription in vitro.

We have studied the liver-specific transcriptional activity of the human transferrin gene promoter. Results of competition experiments, site-directed mutagenesis, and 5' deletion analysis have demonstrated that a TATA box and a binding site for the liver-specific protein Tf-LF1 are the only elements...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:Nucleic Acids Res
Үндсэн зохиолчид: Mendelzon, D, Boissier, F, Zakin, M M
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Oxford University Press 1990
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332305/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2216764/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.19.5717
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