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Modification of pharmacokinetic and abuse-related effects of cocaine by human-derived cocaine hydrolase in monkeys

Although substantial research effort has focused on developing pharmacological treatments for cocaine abuse, no effective medications have been developed. Recent studies show that enzymes that metabolize cocaine in the periphery, forestalling its entry into the brain, can prevent cocaine toxicity an...

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Detalhes bibliográficos
Main Authors: Schindler, Charles W., Justinova, Zuzana, Lafleur, David, Woods, Doug, Roschke, Viktor, Hallak, Hussein, Sklair-Tavron, Liora, Redhi, Godfrey H., Yasar, Sevil, Bergman, Jack, Goldberg, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337883/
https://ncbi.nlm.nih.gov/pubmed/22264200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2011.00424.x
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