Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice

CONTEXT: Inhalation of ambient fine particulate matter (PM(2.5)) is associated with adverse respiratory and cardiovascular effects. A major fraction of PM(2.5) in urban settings is diesel exhaust particulate (DEP), and DEP-induced lung inflammation is likely a critical event mediating many of its ad...

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Auteurs principaux: Weldy, Chad S., White, Collin C., Wilkerson, Hui-Wen, Larson, Timothy V., Stewart, James A., Gill, Sean E., Parks, William C., Kavanagh, Terrance J.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337699/
https://ncbi.nlm.nih.gov/pubmed/21967497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08958378.2011.608095
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