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NK-Dependent Increases in CCL22 Secretion Selectively Recruits Regulatory T Cells to the Tumor Microenvironment

Tumor-induced immune suppression involves the accumulation of immune-suppressive infiltrates in the microenvironment. This study demonstrates increased numbers of CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) in the lungs of C57BL/6 mice bearing a metastatic Lewis lung carcinoma (LLC) variant. Th...

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Detalhes bibliográficos
Main Authors: Mailloux, Adam W., Young, Rita I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337694/
https://ncbi.nlm.nih.gov/pubmed/19234170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801124
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